Recombinant Human CD63 Protein(Halo Tag)

Target Synonym: LAMP-3;MLA1;Granulophysin;Tetraspanin-30

Background: There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 63 (CD63) is a member of the CD family and the transmembrane 4 superfamily,also known as the tetraspanin family. CD63 is a cellular surface glycoprotein characterized by the presence of four bydrophobic domains. CD63 had functions in mediating signal transduction processes and then regulate variety of cellular processes such as cell proliferation, activation and motility. It has reported that CD63 protein associated with tumor progression and served as a blood platlet activation marker and the deficiency of this protein may be associated with Hermansky-Pudlak syndrome.

Bio Activity: Not validated for activity

Sequence: Ala103-Val203

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Calculated MW: 45 kDa

Observed MW: 49 kDa

• SKU: ELSPDMH100469-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100469-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human