Recombinant Human IL17RB Protein(Fc Tag)

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Protein Tag: C-Fc

Uniprot: Q9NRM6

Accession: Q9NRM6

Background: The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Bio Acitivity: Not validated for activity

Sequence: Arg18-Pro292

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 55.1 kDa

Observed MW: 60-80 kDa

• SKU: ELSPDMH100214-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100214-1
• Package Unit: 1 mg
• Quantity Unit: STK