Recombinant Human Kallikrein 3/PSA Protein(His Tag)

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Protein Tag: C-His

Uniprot: P07288

Accession: P07288

Background: KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases. KLK3 contains one peptidase S1 domain. KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence sμggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.

Bio Acitivity: Not validated for activity

Sequence: Met1-Pro261

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 28.6 kDa

Observed MW: 35 kDa

• SKU: ELSPDMH100342-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100342-1
• Package Unit: 1 mg
• Quantity Unit: STK