Recombinant Human PODXL Protein(Fc Tag)

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Protein Tag: C-Fc

Uniprot: O00592

Accession: O00592

Background: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Bio Acitivity: Not validated for activity

Sequence: Ser23-Pro461

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 73.2 kDa

Observed MW: 90-100 kDa

• SKU: ELSPDMH100208-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100208-1
• Package Unit: 1 mg
• Quantity Unit: STK