Recombinant Human SELE Protein(His Tag)

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Protein Tag: C-His

Uniprot: P16581

Accession: P16581

Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin-and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Bio Acitivity: Not validated for activity

Sequence: Met1-Pro556

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 61 kDa

Observed MW: 80-100 kDa

• SKU: ELSPDMH100284-1
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMH100284-1
• Package Unit: 1 mg
• Quantity Unit: STK