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Protein Tag: N-His & C-His
Uniprot: O75865
Accession: O75865-2
Background: TRAPPC6A (trafficking protein particle complex 6A), also known as TRS33 or HSPC289, is a 159 amino acid protein that localizes to the Golgi apparatus and endoplasmic reticulum. Belonging to the TRAPP small subunits family and the BET3 subfamily, TRAPPC6A may play a role in vesicular transport during the biogenesis of melanosomes. TRAPPC6A is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. TRAPPC6A exists as a heterodimer with TRAPPC3 and undergoes alternative splicing to produce two isoforms. TRAPPC6A is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA.
Bio Acitivity: Not validated for activity
Sequence: Met 1-Ser 173
Purity: > 95% as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.
Calculated MW: 18.9 kDa
Observed MW: 20 kDa