Target Synonym: KRT;Cytokeratin;EBS;CK14;EBS3;EBS4;K14;NFJ;Cytokeratin 14;KRT14;ck14;Cytokeratin 14;EBS3;EBS4;K14;Krt14;NFJ;CK 14;CK-14;Cytokeratin14;Cytokeratin-14;Dowling Meara;Dowling-Meara;Epidermolysis bullosa simplex;K1C14;Keratin;Keratin 14;Keratin 14 (epidermolysis bullosa simplex;Keratin type I cytoskeletal 14;Keratin14;Keratin-14;Koebner;Koebner);Krt 14;OTTHUMP00000164624;type I cytoskeletal 14
Background: This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
Immunogen: A synthetic peptide corresponding to the N-terminus of the human Cytokeratin 14.
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:2000;IHC-P 1:10000-1:20000;IP 1-4 μL/mg of lysate
Calculated MW: 52 kDa
Observed MW: 52 kDa