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Recombinant Mouse ANGPTL4 protein (His tag)

Recombinant Mouse ANGPTL4 protein (His tag)
SKU
ELSPDMM100211-100
Packaging Unit
100μg
Manufacturer
Elabscience Biotechnology

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Special promotion: Enjoy a 10% discount on Elabscience recombinant proteins through September 30, 2025.
Promo code: ELABPQ3
No additional discounts available during this period.

Protein Tag: C-His

Uniprot: Q9Z1P8

Accession: Q9Z1P8

Background: Angiopoietin-related protein 4 (ANGPTL4) is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Bio Acitivity: Not validated for activity

Sequence: Lys167-Ser410

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 26.7 kDa

Observed MW: 40 kDa
More Information
SKU ELSPDMM100211-100
Manufacturer Elabscience Biotechnology
Manufacturer SKU PDMM100211-100
Package Unit 100μg
Quantity Unit STK
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