Recombinant Mouse IL-5 Protein(Fc Tag)

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Protein Tag: C-Fc

Uniprot: P04401

Accession: P04401

Background: IL-5 (Interleukin-5) is a secreted cytokine that is expressed as a covalent dimer. It is produced by activated Th2 cells, eosinophils, mast cells, and iNKT cells and promotes eosinophilic and basophilic differentiation and activation. IL-5 signals through a receptor complex containing IL-5 R alpha and the Common beta Chain/CD131 on eosinophils and basophils. Naturally occurring soluble forms of IL-5 R alpha retain the ability to bind IL-5 and limit its bioavailability.

Bio Acitivity: Not validated for activity

Sequence: Met1-Gly133

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 39.5 kDa

Observed MW: 40-60 kDa

• SKU: ELSPDMM100077-500
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMM100077-500
• Package Unit: 500μg
• Quantity Unit: STK