Target Synonym: Paxillin;PXN;entrez:5829
Background: This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
Immunogen: A synthetic phosphopeptide corresponding to residues around Tyr118 of the Human Phospho-Paxillin
Buffer: 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Dilution: WB 1:1000-1:5000
Calculated MW: 65 kDa
Observed MW: 68 kDa