Recombinant Porcine HAVCR1 Protein(hIgG1 Fc Tag)

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Protein Tag: C-hIgG1 Fc

Uniprot: C8CLK5

Accession: C8CLK5

Background: HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest levels in the kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy, and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.

Bio Acitivity: Not validated for activity

Sequence: Tyr21-Val281

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method

Calculated MW: 53.6 kDa

Observed MW: 80-110 kDa

• SKU: ELSPDMP100005-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDMP100005-20
• Package Unit: 20μg
• Quantity Unit: STK