Recombinant Swine IFN gamma protein(His Tag)

Protein Tag: C-His

Uniprot: P17803

Accession: P17803

Background: IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them; leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens; mitogens; or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2; FGF-basic; and EGF.

Bio Acitivity: Measure by its ability to protect PK15 cells infected with encephalomyocarditis (EMC) virus.The ED₅₀ for this effect is <40 pg/mL.

Sequence: Gln 24-Lys 166

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 0.01 EU per μg of the protein as determined by the LAL method.

Calculated MW: 17.7 kDa

Observed MW: 15 kDa

• SKU: ELSPKSS000012-5
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PKSS000012-5
• Package Unit: 5μg
• Quantity Unit: STK
• Application: Cell Culture