Target Synonym: WAP;WFDC;EDDM;Epididymal Secretory Protein E;Putative Protease Inhibitor WAP;Major Epididymis-Specific Protein E;WAP Four-Disulfide Core Domain Protein;dJ461P;WFDC2;EDDM4;HE4;WAP5;dJ461P17.6;Epididymal Secretory Protein E4;Major Epididymis-Specific Protein E4;Putative Protease Inhibitor WAP5;WAP Four-Disulfide Core Domain Protein 2;WAP four-disulfide core domain 2
Background: This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
Immunogen: Recombinant Human WFDC2/HE4 protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:100-1:500