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ADC Related

ADC Related

The ADC, antibody-drug conjugate, a humanised or human monoclonal antibody with conjugated highly potent cytotoxic small molecules (payloads), is a novel therapeutic format with great potential for a paradigm shift in cancer chemotherapy. The three components of the ADC form a powerful oncolytic agent capable of delivering normally untolerated cytotoxins directly to cancer cells, which then internalise and release the cytotoxic drugs. Currently, two ADCs, Adcetris and Kadcyla, have received marketing authorisation and more than 40 others are in clinical development.

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  1. N-Hydroxysulfosuccinimide (sodium), CAS 106627-54-7
    N-Hydroxysulfosuccinimide (sodium), CAS 106627-54-7
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    Sku MEXHY-W002213-1G
    Manufact. SkuHY-W002213-1G
    Packaging Unit1 g
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  2. MC-val-ala-nhs ester, CAS 1895916-22-9
    MC-val-ala-nhs ester, CAS 1895916-22-9
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    Sku MEXHY-W591479-0
    Manufact. SkuHY-W591479-0
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  3. DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
    DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
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    Sku MEXHY-W591408-25
    Manufact. SkuHY-W591408-25
    Packaging Unit25 mg
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  4. 3,4-Dibromo-Mal-PEG4-Acid, CAS 2434639-17-3
    3,4-Dibromo-Mal-PEG4-Acid, CAS 2434639-17-3
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    Sku MEXHY-W591402-0
    Manufact. SkuHY-W591402-0
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  5. DBCO-PEG4-Val-Ala-PAB-PNP, CAS 2348405-93-4
    DBCO-PEG4-Val-Ala-PAB-PNP, CAS 2348405-93-4
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    Sku MEXHY-W591374-0
    Manufact. SkuHY-W591374-0
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  6. DBCO-PEG4-Val-Ala-PAB, CAS 2348405-92-3
    DBCO-PEG4-Val-Ala-PAB, CAS 2348405-92-3
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    Sku MEXHY-W591373-0
    Manufact. SkuHY-W591373-0
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  7. t-Boc-N-amido-PEG4-Val-Cit, CAS 2231240-82-5
    t-Boc-N-amido-PEG4-Val-Cit, CAS 2231240-82-5
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    Sku MEXHY-W800837-0
    Manufact. SkuHY-W800837-0
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  8. Azido-PEG8-Amido-Val-Cit-PAB, CAS 2356229-77-9
    Azido-PEG8-Amido-Val-Cit-PAB, CAS 2356229-77-9
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    Sku MEXHY-W800814-0
    Manufact. SkuHY-W800814-0
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  9. Mal-Amide-PEG4-Val-Cit-PAB-PNP, CAS 2003260-12-4
    Mal-Amide-PEG4-Val-Cit-PAB-PNP, CAS 2003260-12-4
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    Sku MEXHY-W800847-0
    Manufact. SkuHY-W800847-0
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  10. Boc-PEG4-Val-Cit-PAB-OH, CAS 2055024-54-7
    Boc-PEG4-Val-Cit-PAB-OH, CAS 2055024-54-7
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    Sku MEXHY-W800625-0
    Manufact. SkuHY-W800625-0
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