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ADC Related

ADC Related

The ADC, antibody-drug conjugate, a humanised or human monoclonal antibody with conjugated highly potent cytotoxic small molecules (payloads), is a novel therapeutic format with great potential for a paradigm shift in cancer chemotherapy. The three components of the ADC form a powerful oncolytic agent capable of delivering normally untolerated cytotoxins directly to cancer cells, which then internalise and release the cytotoxic drugs. Currently, two ADCs, Adcetris and Kadcyla, have received marketing authorisation and more than 40 others are in clinical development.

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  1. 100mM Pro-Ac, 20 mM Arg, pH 5.0 buffer
    100mM Pro-Ac, 20 mM Arg, pH 5.0 buffer
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    Sku MEXHY-Y1977-10
    Manufact. SkuHY-Y1977-10
    Packaging Unit10 mL
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  2. Propargyl-DOTA-tris(tBu)ester, CAS 911197-00-7
    Propargyl-DOTA-tris(tBu)ester, CAS 911197-00-7
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    Sku MEXHY-W999782-0
    Manufact. SkuHY-W999782-0
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  3. Propargyl-NOTA(tBu)2, CAS 1924677-40-6
    Propargyl-NOTA(tBu)2, CAS 1924677-40-6
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    Sku MEXHY-W999766-0
    Manufact. SkuHY-W999766-0
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  4. TRAP, CAS 1242003-07-1
    TRAP, CAS 1242003-07-1
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    Sku MEXHY-W873634-0
    Manufact. SkuHY-W873634-0
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  5. Maleimide-DTPA, CAS 180152-82-3
    Maleimide-DTPA, CAS 180152-82-3
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    Sku MEXHY-W738256-0
    Manufact. SkuHY-W738256-0
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  6. MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH, CAS 2626930-84-3
    MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH, CAS 2626930-84-3
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    Sku MEXHY-W731085-1
    Manufact. SkuHY-W731085-1
    Packaging Unit1 mg
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  7. γ-Glu-Val-Gly, CAS 38837-70-6
    γ-Glu-Val-Gly, CAS 38837-70-6
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    Sku MEXHY-W614632-10
    Manufact. SkuHY-W614632-10
    Packaging Unit10 mg
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  8. γ-Glu-Val-Gly, CAS 38837-70-6
    γ-Glu-Val-Gly, CAS 38837-70-6
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    Sku MEXHY-W614632-5
    Manufact. SkuHY-W614632-5
    Packaging Unit5 mg
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  9. DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
    DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
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    Sku MEXHY-W591408-5
    Manufact. SkuHY-W591408-5
    Packaging Unit5 mg
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  10. DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
    DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
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    Sku MEXHY-W591408-10
    Manufact. SkuHY-W591408-10
    Packaging Unit10 mg
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