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ADC Related

ADC Related

The ADC, antibody-drug conjugate, a humanised or human monoclonal antibody with conjugated highly potent cytotoxic small molecules (payloads), is a novel therapeutic format with great potential for a paradigm shift in cancer chemotherapy. The three components of the ADC form a powerful oncolytic agent capable of delivering normally untolerated cytotoxins directly to cancer cells, which then internalise and release the cytotoxic drugs. Currently, two ADCs, Adcetris and Kadcyla, have received marketing authorisation and more than 40 others are in clinical development.

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  1. DOTA-PEG10-azide
    DOTA-PEG10-azide
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    Sku MEXHY-164654-0
    Manufact. SkuHY-164654-0
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  2. DOTAEt, CAS 137076-50-7
    DOTAEt, CAS 137076-50-7
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    Sku MEXHY-164653-0
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  3. 3p-C-NOTA, CAS 2166455-20-3
    3p-C-NOTA, CAS 2166455-20-3
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    Sku MEXHY-164603-0
    Manufact. SkuHY-164603-0
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  4. TA-DOTA, CAS 2451069-30-8
    TA-DOTA, CAS 2451069-30-8
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    Sku MEXHY-164599-0
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  5. THP(Bz3)-Glu
    THP(Bz3)-Glu
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    Sku MEXHY-164596-0
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  6. TA-DOTA-GA
    TA-DOTA-GA
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    Sku MEXHY-164594-0
    Manufact. SkuHY-164594-0
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  7. NH-CH2-CH2-DOTAM, CAS 2685840-60-0
    NH-CH2-CH2-DOTAM, CAS 2685840-60-0
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    Sku MEXHY-164593-0
    Manufact. SkuHY-164593-0
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  8. DTPA-tetra(tBu)ester, CAS 180152-83-4
    DTPA-tetra(tBu)ester, CAS 180152-83-4
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    Sku MEXHY-164592-0
    Manufact. SkuHY-164592-0
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  9. THP(Bz)3-NH2, CAS 827331-42-0
    THP(Bz)3-NH2, CAS 827331-42-0
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    Sku MEXHY-164591-0
    Manufact. SkuHY-164591-0
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  10. BCN-NODAGA, CAS 2256055-98-6
    BCN-NODAGA, CAS 2256055-98-6
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    Sku MEXHY-164590-0
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