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Applications: Targeting CD73 has been shown to prevent tumor recurrence and metastases in cancer patients. Anti-CD73 antibodies have been suggested as a new form of personalized cancer therapy.
Description: Anti-CD73 recombinant Human antagonist antibody. This antibody not been tested for cross-reactivity with other species.
Format: Aqueous buffer solution
Formulation: 50 mM Tris-HCl, pH 8.0 138mM NaCl, 2.7 mM KCl.
Purification: Protein A affinity purification from HEK293 supernatants.
Storage Stability: Stable for at least 12 months at -80°C. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4°C, stable for 2 weeks.
Uniprot: P21589
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Deaglio, S., et al., J. Exp. Med. 2007; 204(6): 1257-1265.2. Thompson, L.F., et al., J. Exp. Med. 2004; 200(11): 1395-1405.
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