ADG-106

Product Description: ADG-106 is a fully human agonistic monoclonal IgG4 antibody against CD137 (4-1BB). ADG-106 has the mechanism to activate CD137 via strong FcγRIIB-mediated crosslinking while antagonizing CD137 ligands. The isotype control for ADG-106 can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003)[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Ma Y, et al. Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin's lymphoma. Cell Rep Med. 2024 Feb 20;5(2):101414.

Molecular Weight: N/A

Research Area: Cancer

Target: TNF Receptor

• SKU: MEXHY-P991070-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P991070-0
• Package Unit: Get quote
• Quantity Unit: STK
• Conjugate: Unconjugated