Englumafusp alfa, CAS 2417199-08-5

Product Description: Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion construct comprised of a CD19-specific antibody domain fused to a trimerized extracellular domains of human 41BBL. Englumafusp alfa promotes CD19-specific 4-1BB cross-linking on the surface of T and NK cells[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Antonio Tapia-Galisteo, et al.  Bi- and trispecific immune cell engagers for immunotherapy of hematological malignancies. J Hematol Oncol. 2023 Jul 27;16(1):83./[2]George Fromm, et al. Reconciling intrinsic properties of activating TNF receptors by native ligands versus synthetic agonists. Front Immunol. 2023 Sep 19:14:1236332.

CAS Number: 2417199-08-5

Molecular Weight: N/A

Compound Purity: 99.93

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: CD19

• SKU: MEXHY-P990017-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P990017-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Conjugate: Unconjugated