Product Description: HFB-200301 is an IgG1 antibody targeting tumor necrosis factor receptor 2 (TNFR2). HFB-200301 promotes the activation of TNFR2, thereby activating relevant signaling pathways, such as activating RelA and cRel-containing NF-κB dimers through the classical NF-κB pathway, affecting cell metabolism and gene expression in the presence of sTNF. HFB-200301 is promising for research of cancers[1].
Applications: Cancer-programmed cell death
Formula: N/A
References: [1]Siegmund D, et al. TNF and TNF receptors as therapeutic targets for rheumatic diseases and beyond. Nat Rev Rheumatol. 2023 Sep;19(9):576-591.
Molecular Weight: N/A
Research Area: Cancer
Target: TNF Receptor