Formulation: 200 µg lyophilized peptide
Shelf life (days): 1095
Notes: Peptide sequences: human guanylate cyclase α subunit amino acids 418-436 (EQARAQDGLKKRLGKLKAT) · To be used in conjunction with Cayman’s guanylate cyclase α subunit polyclonal antibody (Catalog No. 160895) to block protein-antibody complex formation during analysis for guanylate cyclase α subunit. · Soluble guanylate cyclase is a heterodimeric enzyme, composed of α and β subunits, that synthesizes cGMP from GTP. The enzyme is activated by the binding of nitric oxide or carbon monoxide to the heme group of the enzyme.{1707} Chronic hypoxia upregulates soluble guanylate expression in rat lung.{7644} The α1 subunit contains 690-717 amino acids and has a molecular mass of 77-82 kDa.{4654,3536,3434} The cloned β1 subunit of guanylate cyclase from human, bovine, and rat sources contains 619 amino acids and has a molecular mass of approximately 70,000.{4654,3535,3531}
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