CAP-100

Product Description: CAP-100 is a monoclonal antibody that targets CCR7. CAP-100 neutralizes the ligand-binding site and signaling of CCR7. CAP-100 strongly inhibits CCR7-induced migration, extravasation, homing, and survival in chronic lymphocytic leukemia (CLL) samples. CAP-100 triggers potent tumor cell killing, mediated by host immune mechanism. CAP-100 shows a favorable toxicity profile on relevant hematopoietic subsets. CAP-100 is involved in research on anti-tumor and disease such as CLL[1].

Formula: N/A

References: [1]Cuesta-Mateos C, et al., Targeting cancer homing into the lymph node with a novel anti-CCR7 therapeutic antibody: the paradigm of CLL. MAbs. 2021 Jan-Dec;13(1):1917484.

Molecular Weight: N/A

Research Area: Cancer; Inflammation/Immunology

Target: CCR

• SKU: MEXHY-P991224-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P991224-0
• Package Unit: Get quote
• Quantity Unit: STK
• Conjugate: Unconjugated