Product Description: ERY-974 is a T-cell-engaging bispecific antibody (TCB) targeting GPC3. ERY-974 binds to both GPC3 and the CD3 receptor on T cells simultaneously, activating T cells and prompting them to release perforin and granzyme, triggering apoptosis of tumor cells. ERY-974 is promising for research of solid tumors, such as liver cancer[1].
Applications: Cancer-programmed cell death
Formula: N/A
References: [1]Liu J, et al. Progresses of T-cell-engaging bispecific antibodies in treatment of solid tumors. Int Immunopharmacol. 2024 Sep 10;138:112609.
Molecular Weight: N/A
Research Area: Cancer
Target: Apoptosis;Glycoprotein VI