EU-103

Product Description: EU-103 is a humanized monoclonal antibody targeting V-Set And Immunoglobulin Domain Containing 4 (VSIG4) with a KD value ranging from 10−7 and 10−9. EU-103 blocks the interaction between VSIG4 and CD8+ T cells, promotes the conversion of M2 macrophages into M1 macrophages, induces the proliferation of CD8+ T cells and the secretion of pro-inflammatory cytokines, thereby inhibiting tumor growth. EU-103 is promising for research of cancers, such as bladder cancer, breast cancer, and colon cancer[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Byoung S. Kwon, et al. Anti-human vsig4 antibodies and uses thereof. WO2020069507A1. 2020-04-02.

Molecular Weight: N/A

Research Area: Cancer

Target: Transmembrane Glycoprotein

• SKU: MEXHY-P991217-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P991217-0
• Package Unit: Get quote
• Quantity Unit: STK
• Conjugate: Unconjugated