Inotuzumab ozogamicin, CAS 635715-01-4

Product Description: Inotuzumab ozogamicin (CMC-544) is an anti-CD22 antibody-drug conjugate (ADC). Inotuzumab ozogamicin consists of a humanized IgG4 anti-CD22 mAb, covalently linked to Calicheamicin (HY-19609) via an acid-labile AcBut (HY-132261) linker. Inotuzumab ozogamicin binds to the minor groove of DNA, inducing double-strand cleavage and subsequent apoptosis. Inotuzumab ozogamicin can be used for the study of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL)[1].

Formula: N/A

References: [1]Bruzzese A, et al. Therapeutic Strategies for Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia in Adult Patients: Optimizing the Use of Monoclonal Antibodies. Eur J Haematol. 2025 Jun;114(6):938-952.

CAS Number: 635715-01-4

Molecular Weight: N/A

Research Area: Cancer

Solubility: H2O

Target: Antibody-Drug Conjugates (ADCs);Apoptosis;CD22;DNA/RNA Synthesis

• SKU: MEXHY-P9959-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P9959-0
• Package Unit: Get quote
• Quantity Unit: STK
• Conjugate: Unconjugated