Clone Name: SPTA1/1810
Light Chain: Kappa
Application Note: IHC-P: 1-2μg/ml for 30 minutes at RT. ELISA: 2-4μg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 280
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [provided by RefSeq, Aug 2017]
Uniprot ID: P02549
Antigen Species: Human
Immunogen: Recombinant human SPTA fragment (around aa356-475) (exact sequence is proprietary)
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: spectrin alpha, erythrocytic 1
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