Target: 4-1BB.
Clone: 3H3.
Specificity: Anti-4-1BB In Vivo Antibody - Ultra Low Endotoxin (3H3) recognizes an epitope on Mouse 4-1BB.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: Activated B cells and T cells, macrophages, and dendritic cells.
Background: Anti-Mouse CD137/4-1BB clone 3H3 is a monoclonal antibody which reacts with mouse 4-1BB, a TNF receptor superfamily member also known as CD137. The 3H3 antibody has been shown to stimulate 4-1BB signaling in vivo.
Immunogen: Unknown.
Concentration: 1.0 - 5.0 mg/ml.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.4, containing no preservatives.
Purity: >98% by SDS-PAGE and HPLC.
Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 1%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.