Anti-Mouse Ly-6G/Ly-6C In Vivo Antibody - Ultra Low Endotoxin (RB6-8C5)

Anti-Mouse Ly-6G/Ly-6C In Vivo Antibody - Ultra Low Endotoxin (RB6-8C5), Host: Rat, Rat IgG2b

Target: Ly-6G/Ly-6C.

Clone: RB6-8C5.

Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution: The Gr-1 antigen is present at various levels correlated with granulocyte differentiation and maturation. The Gr-1 antigen is expressed on other myeloid populations, but not on lymphoid or erythroid cells.

Background: Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. Clone RB6-8C5 antibody has been shown to inhibit the binding of the clone 1A8 antibody. Clone 1A8 monoclonal antibody reacts specifically with mouse Ly6G with no reported cross-reactivity with Ly6C.

Immunogen: Raised against granulocytes of mouse origin.

Concentration: 0.5 mg/ml.

Formulation: No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl.

Purity: >98% by SDS-PAGE and HPLC.

Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method.

Aggregation: Aggregation level ≤ 1%.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.

• SKU: ICH1131UL-5MG
• Manufacturer: Ichorbio
• Manufacturer SKU: ICH1131UL-5MG
• Package Unit: 5mg
• Quantity Unit: STK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Western Blotting, Flow Cytometry, Functional Assay, Immunocytochemistry, In Situ Hybridization
• Isotype: Rat IgG2b
• Host: Rat