Clone Name: MEM-25
Calculated MW: 129
Form: Liquid
Buffer (with preservative): 0.2μm filter-sterilized PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: P20701
Antigen Species: Human
Immunogen: Leukocytes from a pacient suffering from a LGL-type leukaemia.
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: integrin subunit alpha L
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