Clone Name: MEM-59
Application Note: FACS: 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 40
Specificity/Sensitivity: This antibody recognizes neuraminidase-sensitive epitope on CD43 (Leukosialin).
Form: Liquid
Buffer (with preservative): PBS, 15mM Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Notes: For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
Background: This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
Uniprot ID: P16150
Antigen Species: Human
Immunogen: Human T lymphocytes.
Purification: Purified by size-exclusion chromatography
Conjugation: APC-Cy7
Full Name: sialophorin
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