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Application: Useful for studying expression of GPRC5D on the cell surface by flow cytometry.
Background: GPRC5D (orphan G protein–coupled receptor, class C group 5 member D) is a retinoic acid-inducible protein with seven transmembrane segments and a short N-terminal extracellular region. The strong and selective expression of GPRC5D in Multiple Myeloma (MM) cells makes it a promising target for the treatment of this disease. GPRC5D is a CAR (chimeric antigen receptor)-T cell target that has shown promising outcomes.
Clone Number: Monoclonal
Cross Reactivity: This antibody recognizes human GPRC5D. It has not been tested with other species.
Description: The FluoSite™ Anti-GPRC5D Antibody is a purified monospecific antibody, which is labeled with R-Phycoerythrin (PE). This antibody has been tested by flow cytometry for binding to human GPRC5D (orphan G protein–coupled receptor, class C group 5 member D) on GPRC5D HEK293 Cell Line (BPS Bioscience #78345). FluoSite™ is a tag-based method for site-specific conjugation of antibodies with fluorophores, ensuring the labeling site is far from the antigen-binding domain to preserve antibody functionality. This precise, consistent labeling ensures the homogeneity of the labeled antibody preparation, making it ideal for flow cytometry and other high-sensitivity applications.
Format: Aqueous buffer solution.
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 0.09% Sodium Azide, 0.2% BSA, and up to 20% glycerol. May contain a protein stabilizer.
Purification: Protein A affinity chromatography from HEK293 supernatants.
Purity: ≥90%
Storage Stability: At least 6 months at 4°C. Protect from prolonged exposure to light. DO NOT FREEZE. The antibody solution should be stored undiluted between 2°C and 8°C.
Target: GPRC5D
Uniprot: Q9NZD1
Warnings: Do not freeze. Protect from light.
Biosafety Level: Not applicable (BSL-1)
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