Clone Name: GFAP/2076
Light Chain: Kappa
Application Note: WB: 1-2μg/ml. IHC-P: 1-2μg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 50
Specificity/Sensitivity: This MAb recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Uniprot ID: P14136
Antigen Species: Human
Immunogen: Recombinant human GFAP protein fragment (around aa 101-200) (exact sequence is proprietary)
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: glial fibrillary acidic protein
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