Target: parvalbumin.
Conjugate: RPE.
Product Type: Monoclonal.
Clone Number: C12.
Immunogen: Synthetic peptide from the full length Rat Parvalbumin protein.
Swiss-Prot: P02625.
Purification: Protein A Purified.
Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide.
Concentration: 1mg/ml.
Specificity: Detects 12 kDa.
Cellular Localization: Cytoplasmic vesicle membrane.
Tissue Specificity: Retina. Expressed throughout the horizontal cells and/or terminals.
Scientific Background: Parvalbumin is involved in calcium signaling. Alterations in the function of parvalbumin-expressing neurons have been implicated in Alzheimer's, autism, schizophrenia, age-related cognitive defects and some forms of cancer (1).
References: 1. Cates. M.S., Teodoro M.L., Phillips G.N. (2002) Biophys J. 82(3): 1133-1146.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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