Target Synonym: UNQ;SLAM Family Member;SLAMF;SLAMF6;CD352;KALI;KALIb;Ly108;NTB-A;NTBA;SF2000;Activating NK Receptor;NK-T-B-Antigen;SLAM Family Member 6;UNQ6123;PRO20080;NTB-A;KAL1;Ly108
Background: NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.
Immunogen: Recombinant Human Ly108 / SLAMF6 protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:100-1:500;
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