Target Synonym: RPS6KA;HU-1;MAPKAPK1A;RSK;RSK1;p90Rsk;RPS6KA1;90 kDa ribosomal protein S6 kinase 1;90kD;dJ590P13.1;dJ590P13.1 (ribosomal protein S6 kinase;EC 2.7.11.1;HU 1;HU1;KS6A1;MAP kinase activated protein kinase 1a;MAP kinase-activated protein kinase 1a;MAPK-activated protein kinase 1a;MAPKAP kinase 1a;MAPKAPK-1a;MGC79981;Mitogen-activated protein kinase-activated protein kinase 1A;OTTHUMP00000004113;p90 RSK1;p90-RSK 1;p90RSK1;p90S6K;polypeptide 1;pp90RSK1;Ribosomal protein S6 kinase 90kD 1;Ribosomal protein S6 kinase 90kD polypeptide 1;Ribosomal protein S6 kinase 90kDa polypeptide 1;Ribosomal protein S6 kinase alpha 1;Ribosomal protein S6 kinase alpha-1;Ribosomal protein S6 kinase polypeptide 1;Ribosomal S6 kinase 1;RPS6K1 alpha;RSK 1;RSK 1 p90;RSK-1;S6K alpha 1;S6K-alpha-1
Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 1 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen: A synthetic peptide corresponding to the residues around (Thr359, Ser363) of Human p90RSK
Buffer: 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Dilution: WB 1:10000-1:100000;
Calculated MW: 83 kDa
Observed MW: 83 kDa
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