Clone Name: HL3616
Light Chain: Kappa
Calculated MW: 72
Specificity/Sensitivity: This antibody detects Syk protein when dually phosphorylated at Tyr525 and Tyr526, and it also reacts with Syk protein when singly phosphorylated at Tyr525 or Tyr526.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml
Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Uniprot ID: P43405
Antigen Species: Human
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Tyr525/Tyr526 of human Syk. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: spleen associated tyrosine kinase
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