Clone Name: TCF4/1705
Light Chain: Kappa
Application Note: WB: 1-2μg/ml. ELISA: 2-4μg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 71
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016]
Uniprot ID: P15884
Antigen Species: Human
Immunogen: Recombinant human TCF4 protein fragment (around aa 365-671) (exact sequence is proprietary)
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: transcription factor 4
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