Target Synonym: FCG;CDw;Fcgr;IGFR;FCGR2B;CD32;CD32B;FCG2;FCGR2;IGFR2;CDw32;Fc-gamma-RIIb;FcRII-b;Low affinity immunoglobulin gamma Fc region receptor II-b;IgG Fc receptor II-b;Fc-gamma RII-b;CD32 antigen;Fc fragment of IgG;Fc gamma receptor IIB;Fc gamma RII;Fc gamma RIIB;FCG2B;Fc-gamma RII;FCRII;FcγRⅡ;IgG Fc receptor II beta;low affinity II;low affinity IIb;Low affinity immunoglobulin gamma Fc region receptor II;Ly-17;Lym 1;Lymphocyte antigen 17;receptor;receptor (CD32);receptor for;receptor for (CD32)
Background: Fc gamma RII, also known as CD32, is a group of three closely related proteins (Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIC) that share greater than 94% amino acid identity in their extracellular domains with Fc gamma RIIB and Fc gamma RIIC having identical extracellular domains. They function as transmembrane receptors for the Fc portion of IgG molecules. These proteins are expressed by various hematopoietic cells including monocytes, macrophages, neutrophils, NK, T and B cells. The Fc gamma RII proteins are involved in phagocytosis of immune complexes and modulation of antibody production by B cells.
Buffer: PBS, pH 7.2. Contains 0.05% proclin 300.
Immunogen: Recombinant Human CD32 protein
Dilution: FCM 2 μg/mL(1×105-5×105 cells)
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