Target Synonym: GIG;MORT;Hematopoietic progenitor cell antigen CD;Gp105;CD34;CD34 molecule;GIG3;MORT1;Gp105-120;My10;Hematopoietic progenitor cell antigen CD34;Mucosialin;CD34;CD34 molecule;GIG3;MORT1;RP11-328D5.2
Background: CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
Buffer: PBS, pH 7.2. Contains 0.05% proclin 300.
Immunogen: Recombinant Human CD34 protein
Dilution: FCM 2 μg/mL(1×105-5×105 cells)
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