Recombinant DPY30 domain containing 2/DYDC2 Monoclonal Antibody

Target Synonym: DYDC;DYDC2

Background: DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. As part of the MLL1/MLL complex, DPY30 domain containing 2 is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 domain containing 2 may also play an indirect or direct role in endosomal transport.

Immunogen: Recombinant Human DPY30 domain containing 2/DYDC2 Protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: ICC/IF 1:20-1:100

• SKU: ELSAN300445P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: AN300445P-100
• Package Unit: 100μL
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunofluorescence, Immunocytochemistry
• Isotype: IgG
• Host: Rabbit
• Conjugate: Unconjugated