RO7122290

Product Description: RO7122290 is a bispecific fusion protein carrying a split trimeric 4-1BB (CD137) ligand and a fibroblast activation protein α (FAP) binding site. O7122290 is a FAP-α-targeted 4-1BB agonist that costimulates T cells for improved tumor cell killing in FAP-expressing tumors[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Melero I, et al. A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors. Sci Transl Med. 2023 May 10;15(695):eabp9229.

Molecular Weight: N/A

Research Area: Cancer

Target: FAP

• SKU: MEXHY-P991087-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P991087-0
• Package Unit: Get quote
• Quantity Unit: STK
• Conjugate: Unconjugated