Elab Fluor® 647 Anti-Mouse CD163 Antibody(S15049F)

Target Synonym: MM130SCARI1;M130

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/L0eLWD

Citation Link 2: C57BL/6 murine bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor^® 647 Anti-Mouse CD163 Antibody (Left). Bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor^® 647 Rat IgG2a,κ Isotype Control (Right).

Background: CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1295M-50
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1295M-50
• Package Unit: 50 Tests
• Quantity Unit: PAK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rat IgG2a κ
• Human Gene ID: 93671
• Host: Rat
• Conjugate: Conjugated, Elab Fluor647