Elab Fluor® Red 780 Anti-Mouse CD49b/pan-NK cells Antibody(DX5)

Target Synonym: CD49 antigen-like family member B;CD49b;Collagen receptor;GPIa;Integrin alpha-2;Platelet membrane glycoprotein Ia;VLA-2 subunit alpha

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10⁶ cells in 100 μL volume].

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/K8qvr5

Citation Link 2: C57BL/6 murine splenocytes are stained with FITC Anti-Mouse NK1.1 Antibody and Elab Fluor^® Red 780 Anti-Mouse CD49b Antibody (Left). Splenocytes are stained with FITC Anti-Mouse NK1.1 Antibody and Elab Fluor^® Red 780 Rat IgM, κ Isotype Control (Right).

Background: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1116US-25
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1116US-25
• Package Unit: 25μg
• Quantity Unit: STK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rat IgM κ
• Human Gene ID: 16398
• Host: Rat
• Conjugate: Conjugated, Elab Fluor Red 780