Elab Fluor® Violet 450 Anti-Human CD62L Antibody(HI62L)

Target Synonym: CD62L;CD62antigen-likefamilymemberL;L-selectin;LAM-1;LECAM1;Lnhr;Ly-22;Ly22;Lymphnodehomingreceptor;Sell

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Citation Link 1: https://789.bio/ec/iDejXD

Citation Link 2: Human peripheral blood lymphocytes are stained with APC Anti-Human CD4 Antibody and Elab Fluor^® Violet 450 Anti-Human CD62L Antibody[HI62L] (Left). Lymphocytes are stained with APC Anti-Human CD4 Antibody and Elab Fluor^® Violet 450 Mouse IgG2a, κ Isotype Control (Right).

Background: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1336Q-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1336Q-100
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG2a κ
• Host: Mouse
• Conjugate: Conjugated, Elab Fluor Violet 450