Target Synonym: Ly-6A.2/Ly-6E.1;Ly6;Ly6a;SCA-1;TAP
Usage: Each lot of this antibody is quality control tested by flow cytometric analysis.
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation Link 1:
https://789.bio/ec/nDybP4Citation Link 2:
C57BL/6 murine bone marrow cells are stained with APC Anti-Mouse CD117 Antibody and Elab Fluor® Violet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody (Left). Bone marrow cells are stained with APC Anti-Mouse CD117 Antibody and Elab Fluor® Violet 450 Rat IgG2a, κ Isotype Control (Right). Background: Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
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