Product Description: STX-100 is a humanized antibody expressed in CHO cells, targeting Integrin aVb6 (ITGAV & ITGB6). STX-100 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.12 kDa. The isotype control for STX-100 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Applications: COVID-19-immunoregulation
References: [1]Violette S, et al. Identification Of Biomarkers To Monitor The Activity Of STX-100, A Humanized Anti-±v²6 Antibody, In A Phase 2a Trial In Idiopathic Pulmonary Fibrosis[M]//B28. EMERGING BIOMARKERS OF COMPLEX LUNG DISEASES. American Thoracic Society, 2012: A2659-A2659.
CAS Number: 1439902-67-6
Compound Purity: 99.99
Research Area: Inflammation/Immunology
Target: Integrin