Tilvestamab, CAS 2226775-26-2

Product Description: Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas[1].

Applications: Cancer-Kinase/protease

Formula: N/A

References: [1]Chen TJ, et al. AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model. Physiol Rep. 2021 Dec;9(23):e15140.

CAS Number: 2226775-26-2

Molecular Weight: (146.16 kDa)

Compound Purity: 98.08

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: TAM Receptor

• SKU: MEXHY-P99161-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99161-25
• Package Unit: 25 mg
• Quantity Unit: STK
• Conjugate: Unconjugated