TRX-518

Product Description: TRX-518 is a humanized agonist antibody targeting glucocorticoid-induced tumor necrosis factor receptor (GITR). TRX-518 specifically targets GITR⁺ Tregs and CD45RA⁻Foxp3⁺ effector Tregs (eTregs) among regulatory T cells (Tregs), reducing the number of Tregs in circulation and within tumors. TRX-518 is promising for research of cancers[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Zappasodi R, et al. Abstract CT018: Intratumor and peripheral Treg modulation as a pharmacodynamic biomarker of the GITR agonist antibody TRX-518 in the first in-human trial[J]. Cancer Research, 2017, 77(13_Supplement): CT018-CT018.

Molecular Weight: N/A

Research Area: Cancer

Target: TNF Receptor

• SKU: MEXHY-P991180-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P991180-0
• Package Unit: Get quote
• Quantity Unit: STK
• Conjugate: Unconjugated