Antibodies

Antibodies represent an important tool in basic research as well as in diagnostic and more frequently in therapeutic applications. There are many methods, based on the unique binding capacity and the ability of antibodies to detect, identify or localize the specific target. Antibodies might be divided into primary antibodies, which recognize a specific target, and secondary antibodies, which bind to primary antibodies. Based on their origin, antibodies might be monoclonal, polyclonal or recombinant.

Chemically, antibodies are proteins with molecular weight around 150 kDa, carrying sugar (glycan) residues. Structurally they form a “Y” shape with 2 heavy and 2 light polypeptide chains. Every antibody has a constant domain, which is same for all antibodies of the same isotype, and a variable domain.

Szabo-Scandic offers a broad range of antibodies for all applications including immunoblotting (Western blot), flow cytometry, immunohistochemistry, immunocytochemistry, immunoprecipitation, enzyme immunoassays and functional assays.