16α-Hydroxyprednisolone-d3

Product Description: 16α-Hydroxyprednisolone-d3 is the deuterium labeled 16α-Hydroxyprednisolone. 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes[1][2].

Formula: C21H25D3O6

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Xavier Matabosch, et al. Identification of budesonide metabolites in human urine after oral administration. Anal Bioanal Chem. 2012 Aug;404(2):325-40./[3]G Jönsson, et al. Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. Drug Metab Dispos. 1995 Jan;23(1):137-42.

Molecular Weight: 379.46

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Drug Metabolite;Isotope-Labeled Compounds

• SKU: MEXHY-117580S-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-117580S-10
• Package Unit: 10 mg
• Quantity Unit: STK